Deflazacort: Warnings of Deflazacort

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Deflazacort can cause fluid and salt retention and so may oppose the effects of the following medicines: antihypertensive medicines used to treat high blood pressure, diuretics, e.g. furosemide. Deflazacort should be taken in the morning to mimic the natural production of corticosteroids by the body. They should be taken after food to minimize irritation to the stomach.

- You must not stop taking this medicine suddenly if you have been taking it for more than three weeks. This is because long-term use of corticosteroids can suppress the natural production of corticosteroids by the adrenal glands, which means that the body becomes temporarily reliant on the medicine.

- You will be given a steroid card with this medicine that you should carry with you at all times. Show it to anyone who treats you .

- During times of physical stress, for example illnesses, trauma or surgery, your adrenal glands would normally produce more steroid hormones to cope.

- Corticosteroids decrease the body's natural immune and inflammatory responses. They may increase your susceptibility to infections and can also mask the symptoms of infections, making you think they are less serious than they are.

- If you have never had chickenpox you could be at risk of severe chickenpox while having treatment with this medicine and should avoid close personal contact with people who have chickenpox or shingles .

Deflazacort should be used with caution in patients with adrenal suppression and children and adolescents ; frequent monitoring required if history of tuberculosis , hypertension, recent myocardial infarction , congestive heart failure, liver failure, renal impairment.